The administration of non-psychotropic plant cannabinoids, in particular cannabidiol (CBD), inhibit proliferation and selectively trigger cell suicide of prostate carcinoma, according to preclinical data to be published in the British Journal of Pharmacology. (Read the study abstract online here.)
An international team of investigators from Italy and the United Kingdom assessed the anti-cancer properties of various non-psychoactive synthetic and botanical cannabinoids, including CBD, CBG (cannabigerol), CBN (cannabinol) and THCV (tetrahydrocannabivarin), in vivo and in vitro (in culture).
Researchers reported, “The … data presented here allow us to suggest that non-THC cannabinoids, and CBD in particular, retard proliferation and cause apoptosis (programmed cell death) of prostate carcinoma growth via a combination of cannabinoid receptor-independent cellular and molecular mechanisms. … We suggest that non-THC cannabinoids … might provide the basis for the development of novel therapeutic strategies for the treatment of prostate carcinoma.”
Prostate cancer is the second most common cancer in American men. It is the second leading cause of cancer death in American males, trailing only behind lung cancer.